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Structure of 33332-29-5
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5-Chloropyrazin-2-amine serves as a key heterocyclic scaffold in medicinal chemistry, offering a reactive site for cross-coupling and functionalization. The chlorine atom enables direct substitution under palladium-catalyzed conditions, while the pyrazine ring provides enhanced metabolic stability and favorable electronic properties for target engagement. This compound integrates readily into bioactive molecules requiring electron-deficient aromatic systems.
5-Chloropyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrazine-based heterocycles. Its chlorine substituent facilitates nucleophilic substitution reactions, while the pyrazin-2-amine core provides a handle for further functionalization via coupling protocols. The compound exhibits good bench stability and compatibility with standard reaction conditions, making it well-suited for iterative synthesis workflows in API development and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: