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CS-W001157 4
Total: USD 88.00

ethyl 2-aminonicotinate

  • CAS No. 13362-26-0

  • Cat. No. CS-W002788
  • Purity≥98%
  • MDL No.MFCD01569452

*For research and further manufacturing use only, not for direct human use.

ethyl 2-aminonicotinate|CS-W002788

Structure of 13362-26-0

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General Information

  • CAS No. 13362-26-0
  • Cat. No. CS-W002788
  • Purity ≥98%
  • MDL No. MFCD01569452
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) Ethyl 2-Aminopyridine-3-carboxylate
  • SMILES CCOC(=O)c1cccnc1N

Description

Ethyl 2-aminonicotinate features a strategically positioned amino group ortho to the ester, enabling direct functionalization in heterocyclic synthesis. This bench-stable derivative delivers enhanced reactivity in transition-metal-catalyzed couplings and serves as a key intermediate in pharmaceutical scaffold development.

Synthesis

  • Route1
    • In-stock
      NSC 3049|CS-W008765
      5345-47-1
    • null|null
      64-17-5
    • ~99%
    • In-stock
      ethyl 2-aminonicotinate|CS-W002788
      13362-26-0

    References

    • WO2008/82490 A2, ; Page/Page column 70 ; WO 2008/082490 A2
  • Route2
    • null|null
      199734-00-4
    • ~%
    • In-stock
      ethyl 2-aminonicotinate|CS-W002788
      13362-26-0

    References

    • Tetrahedron Letters, , vol. 54, # 5 p. 414 - 418
  • Route3
    • In-stock
      NSC 3049|CS-W008765
      5345-47-1
    • null|null
      75-03-6
    • ~%
    • In-stock
      ethyl 2-aminonicotinate|CS-W002788
      13362-26-0

    References

    • EP2168959 A1, ; Page/Page column 79-80 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   0.8405
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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