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Structure of 1340372-11-3
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This pyrazole carboxylic acid features a tetrahydropyran-4-yl group that enhances solubility and metabolic stability. The scaffold integrates a polar heterocycle with a rigid, oxygen-containing ring, enabling robust conjugation in medicinal chemistry. Designed for efficient derivatization, it serves as a versatile building block in target-oriented synthesis.
1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based heterocycles with enhanced solubility and metabolic stability. The tetrahydropyran-4-yl group provides a robust, bench-stable protecting group for the alcohol functionality, facilitating orthogonal deprotection during synthesis. Its carboxylic acid moiety supports direct coupling reactions, amide formation, or salt formation, making it suitable for peptide-like conjugations and scaffold diversification in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: