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CS-W001157 4
Total: USD 88.00

(R)-tert-butyl 2-formylpiperidine-1-carboxylate

  • CAS No. 134526-69-5

  • Cat. No. CS-0005349
  • Molecule weight213.27
  • Purity≥98%
  • MDL No.MFCD06738714

*For research and further manufacturing use only, not for direct human use.

(R)-tert-butyl 2-formylpiperidine-1-carboxylate|CS-0005349

Structure of 134526-69-5

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General Information

  • CAS No. 134526-69-5
  • Cat. No. CS-0005349
  • Purity ≥98%
  • MDL No. MFCD06738714
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₃
  • Molecular Weight 213.27
  • Synonym(s) tert-butyl (2R)-2-forMylpiperidine-1-carboxylate
  • SMILES O=C(OC(C)(C)C)N(CCCC1)[C@H]1C=O

Synthesis

  • Route1
    • (R)-tert-Butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate|CS-0715665
      203056-15-9
    • ~94%
    • In-stock
      (R)-tert-butyl 2-formylpiperidine-1-carboxylate|CS-0005349
      134526-69-5

    References

    • BRISTOL-MYERS SQUIBB COMPANY; SUN, Chongqing; EWING, William R.; BOLTON, Scott A.; GU, Zhengxiang; HUANG, Yanting; MURUGESAN, Natesan; ZHU, Yeheng Patent: WO2012/125622 A1, 2012 ; Location in patent: Page/Page column 123 ; WO 2012/125622 A1
  • Route2
    • (R)-1-tert-Butyl 2-methyl piperidine-1,2-dicarboxylate|CS-0041508
      164456-75-1
    • ~65%
    • In-stock
      (R)-tert-butyl 2-formylpiperidine-1-carboxylate|CS-0005349
      134526-69-5

    References

    • AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/259862 A1, 2007 ; Location in patent: Page/Page column 11 ; US 20070259862 A1
  • Route3

    References

    • Alibes, Ramon; Ballbe, Marta; Busque, Felix; De March, Pedro; Elias, Laia; Figueredo, Marta; Font, Josep Organic Letters, 2004 , vol. 6, # 11 p. 1813 - 1816

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.61
  • LogP   1.9749
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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