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Structure of 1345866-66-1
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This tetrazine-functionalized benzoic acid enables efficient bioorthogonal conjugation via inverse electron-demand Diels-Alder reactions. The methyl-substituted tetrazine moiety enhances reaction kinetics while maintaining stability under physiological conditions. Designed for direct integration into peptide and protein labeling workflows, the carboxylic acid group facilitates straightforward coupling to amine-containing biomolecules.
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds. The tetrazine core enables efficient inverse electron-demand Diels–Alder reactions with strained dienophiles, facilitating rapid conjugation in synthetic and medicinal chemistry workflows. The carboxylic acid functionality provides direct handle for derivatization, while the methyl-substituted tetrazine offers enhanced bench stability and predictable reactivity. This compound functions effectively in modular synthesis of targeted pharmaceutical intermediates and probe molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: