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Structure of 13472-56-5
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2-Methoxy-5-methylpyridine is a bench-stable, electron-rich heterocycle featuring complementary methoxy and methyl substituents at ortho positions relative to the nitrogen. This configuration enhances solubility in organic media while maintaining thermal resilience. The molecule serves as a pivotal scaffold for ligand design, pharmaceutical intermediates, and functional materials, enabling efficient coupling under standard cross-coupling conditions.
2-Methoxy-5-methylpyridine serves as a versatile building block in medicinal chemistry, offering a well-defined pyridine scaffold with orthogonal functional handles. The methoxy group enables electrophilic substitution or Suzuki coupling under standard conditions, while the methyl substituent provides a site for directed ortho-metalation or oxidation to carboxylic acid derivatives. Bench-stable and amenable to purification via flash chromatography, it functions reliably in multistep syntheses of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: