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Structure of 863578-21-6
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This boronate ester integrates a chloro-substituted aniline scaffold, enabling direct coupling in Suzuki-Miyaura reactions. The tetramethyl-1,3,2-dioxaborolane moiety confers stability and enhanced reactivity under standard conditions. Designed for efficient C–N bond formation, this reagent facilitates rapid access to functionalized arylamines in synthetic workflows.
5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pendant boronate ester enables efficient C–C bond formation under mild conditions, while the chloro and amine groups provide orthogonal reactivity for sequential functionalization. Bench-stable and readily purified by standard chromatography, it functions as a key intermediate in the synthesis of biaryl scaffolds and functionalized heterocycles relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: