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CS-W001157 4
Total: USD 88.00

Boc-NH-PEG5-CH2CH2COOH

  • CAS No. 1347750-78-0

  • Cat. No. CS-0040953
  • Purity≥97%
  • MDL No.MFCD24539478
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG5-CH2CH2COOH|CS-0040953

Structure of 1347750-78-0

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Description

Boc-NH-PEG5-CH2CH2COOH features a tert-butoxycarbonyl-protected amine terminus linked to a five-ethylene glycol spacer, culminating in a terminal carboxylic acid. This bifunctional scaffold enables site-specific conjugation via amide bond formation, while the PEG5 chain imparts solubility and reduces aggregation in aqueous environments. Ideal for bioconjugation workflows requiring stability and controlled functional group presentation.

Application

Boc-NH-PEG5-CH₂CH₂COOH serves as a versatile bifunctional linker for conjugation and solid-phase synthesis. The Boc-protected amine enables stable storage and orthogonal deprotection, while the terminal carboxylic acid facilitates efficient coupling via standard amide bond formation. The five-ethylene glycol (PEG5) spacer provides enhanced solubility and reduced aggregation, improving accessibility in aqueous and biological environments. This compound functions reliably in peptide modification, antibody-drug conjugate assembly, and functionalized nanoparticle synthesis.

General Information

  • CAS No. 1347750-78-0
  • Cat. No. CS-0040953
  • Purity ≥97%
  • MDL No. MFCD24539478
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₅NO₉
  • Molecular Weight 409.47
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(O)=O

Computational Chemistry Data

  • TPSA   121.78
  • LogP   1.0688
  • H_Acceptors   8
  • H_Donors   2
  • Rotatable_Bonds   18

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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