Amino-PEG3-CH2COOH

Name: Amino-PEG3-CH2COOH
Brand: ChemScene
Availability: InStock
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CAS No. 134978-99-7
Cat. No. CS-0115122
Purity≥96%
MDL No.MFCD24479841

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

Amino-PEG3-CH2COOH is a bifunctional PEG-based linker featuring a primary amine at one terminus and a carboxylic acid at the other. This combination enables efficient conjugation to biomolecules via amide bond formation or coupling to activated esters, facilitating site-specific bioconjugation in protein labeling, drug delivery systems, and surface functionalization. The three-ethylene glycol repeat units provide enhanced solubility and reduced non-specific binding in aqueous environments.

Application

Amino-PEG3-CH2COOH serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the solubility and biocompatibility of PEG with reactive amine and carboxylic acid termini. The triethylene glycol spacer provides enhanced flexibility and hydrophilicity, while the terminal groups enable efficient coupling to biomolecules, surfaces, or resins via standard amide or NHS ester chemistry. This compound facilitates robust, site-specific functionalization in drug delivery systems, bioconjugates, and surface-modified materials.

General Information

CAS No. 134978-99-7
Cat. No. CS-0115122
Purity ≥96%
MDL No. MFCD24479841
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₇NO₅
Molecular Weight 207.22
Synonym(s) None
SMILES O=C(O)COCCOCCOCCN

Computational Chemistry Data

TPSA 91.01
LogP -0.9205
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 10

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

Quality Control

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Other Classifications

Building Blocks Functional Group PEG

Building Blocks Skeleton Fatty chain compounds

Life Science Linker Amino PEG

Life Science Linker PEG Acid

Life Science PROTAC PROTAC Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Amino-PEG3-CH2COOH

CAS No. 134978-99-7

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