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Imidazo[1,2-a]pyridin-6-ylmethanamine dihydrochloride

  • CAS No. 1352305-21-5

  • Cat. No. CS-0099160
  • Purity≥95%
  • MDL No.MFCD20921662

*For research and further manufacturing use only, not for direct human use.

Imidazo[1,2-a]pyridin-6-ylmethanamine dihydrochloride|CS-0099160

Structure of 1352305-21-5

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General Information

  • CAS No. 1352305-21-5
  • Cat. No. CS-0099160
  • Purity ≥95%
  • MDL No. MFCD20921662
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁Cl₂N₃
  • Molecular Weight 220.10
  • Synonym(s) C-Imidazo[1,2-a]pyridin-6-yl-methylamine hydrochloride
  • SMILES NCC1=CN2C(C=C1)=NC=C2.[H]Cl.[H]Cl

Description

Imidazo[1,2-a]pyridin-6-ylmethanamine dihydrochloride features a rigid heteroaromatic core with a primary amine handle, enabling direct incorporation into bioactive molecule scaffolds. The dihydrochloride salt enhances solubility and stability in aqueous media, facilitating use in medicinal chemistry campaigns and combinatorial synthesis workflows.

Application

Imidazo[1,2-a]pyridin-6-ylmethanamine dihydrochloride serves as a versatile building block for medicinal chemistry and catalytic synthesis. The compound enables efficient construction of nitrogen-rich heterocyclic scaffolds due to its reactive amine functionality and compatibility with standard coupling protocols. Its dihydrochloride salt form enhances solubility and stability in aqueous and polar organic media, facilitating purification and handling in high-throughput workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.32
  • LogP   1.6366
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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