4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthonitrile

Name: 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1352794-90-1
Cat. No. CS-0013443
Purity≥97%
MDL No.MFCD28167500

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthonitrile|CS-0013443

Structure of 1352794-90-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This boronate-functionalized naphthalene derivative features a stable tetramethylboronate group that enables efficient Suzuki-Miyaura coupling under mild conditions. The nitrile substituent enhances electron-withdrawing character, facilitating conjugation and enabling precise functionalization in complex molecular architectures.

Application

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthonitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The naphthonitrile moiety provides a rigid, electron-deficient scaffold ideal for constructing biaryl and heterocyclic frameworks. The pinacol boronate group ensures excellent stability, ease of handling, and compatibility with diverse reaction conditions, enabling efficient C–C bond formation in medicinal chemistry and materials synthesis.

General Information

CAS No. 1352794-90-1
Cat. No. CS-0013443
Purity ≥97%
MDL No. MFCD28167500
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₇H₁₈BNO₂
Molecular Weight 279.14
Synonym(s) 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene-1-carbonitrile
SMILES CC1(C)OB(OC1(C)C)C2=CC=C(C#N)C3=C2C=CC=C3

Computational Chemistry Data

TPSA 42.25
LogP 3.01068
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Naphthalene compounds

Key Words

1352794-90-1 sigma1352794-90-1 manufacturer1352794-90-1 price1352794-90-1 structure1352794-90-1 SDSbuy 1352794-90-11352794-90-1 supplier1352794-90-1 uses1352794-90-1 molecular weightprice of 1352794-90-11352794-90-1 chemical name formula of 1352794-90-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthonitrile

CAS No. 1352794-90-1

Recommended Products