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CS-W001157 4
Total: USD 88.00

5,7-Dichloro-3-iodopyrazolo[1,5-a]pyrimidine

  • CAS No. 754211-05-7

  • Cat. No. CS-0471551
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,7-Dichloro-3-iodopyrazolo[1,5-a]pyrimidine|CS-0471551

Structure of 754211-05-7

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General Information

  • CAS No. 754211-05-7
  • Cat. No. CS-0471551
  • Purity ≥96%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₂IN₃
  • Molecular Weight 313.91
  • Synonym(s) None
  • SMILES ClC1=NC2N(N=CC=2I)C(Cl)=C1

Description

5,7-Dichloro-3-iodopyrazolo[1,5-a]pyrimidine features a rigid heterocyclic core with strategically positioned halogens enabling efficient cross-coupling reactions. The electron-deficient pyrazolopyrimidine scaffold supports rapid functionalization in late-stage derivatization, while the iodine moiety ensures high reactivity under palladium catalysis. This compound serves as a key intermediate for bioactive molecule synthesis.

Application

5,7-Dichloro-3-iodopyrazolo[1,5-a]pyrimidine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. The dichloro substitution pattern enhances electrophilic reactivity at C5 and C7, while the iodine at C3 enables palladium-catalyzed cross-coupling reactions. This compound exhibits excellent bench stability and facilitates efficient functionalization in late-stage diversification workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.6407
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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