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CS-W001157 4
Total: USD 88.00

2-Amino-3-bromopyridine

  • CAS No. 13534-99-1

  • Cat. No. CS-W019714
  • Purity≥98%
  • MDL No.MFCD03095187

*For research and further manufacturing use only, not for direct human use.

2-Amino-3-bromopyridine|CS-W019714

Structure of 13534-99-1

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General Information

  • CAS No. 13534-99-1
  • Cat. No. CS-W019714
  • Purity ≥98%
  • MDL No. MFCD03095187
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BrN₂
  • Molecular Weight 173.01
  • Synonym(s) 2-amino-3-bromopyridinium
  • SMILES NC1=NC=CC=C1Br

Application

2-Amino-3-bromopyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its ortho-halogen and amino functionality. The bromine atom facilitates Suzuki, Stille, and Negishi couplings, while the amino group offers direct derivatization potential. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing nitrogen-containing heterocyclic scaffolds in API development.

Synthesis

  • Route1
    • null|null
      239137-57-6
    • ~92%
    • In-stock
      2-Amino-3-bromopyridine|CS-W019714
      13534-99-1

    References

    • Iwaki, Takehiko; Yasuhara, Akito; Sakamoto, Takao Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 11 p. 1505 - 1510
  • Route2

    References

    • US5593993 A1, ;
  • Route3

    References

    • Malinowski, Marek Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 1 p. 51 - 54

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.4263
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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