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Structure of 135380-24-4
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6-Methyl-2,6-diazaspiro[3.4]octane features a rigid spirocyclic core with strategically positioned nitrogen atoms and a methyl substituent that enhances lipophilicity and conformational stability. This scaffold delivers enhanced metabolic resistance and favorable binding kinetics in medicinal chemistry applications.
6-Methyl-2,6-diazaspiro[3.4]octane serves as a rigid, bicyclic scaffold for medicinal chemistry applications, offering enhanced conformational control and metabolic stability. The spirocyclic framework provides orthogonal nitrogen sites for derivatization, while the methyl group at C6 improves solubility and steric profile. This compound enables efficient access to diverse heterocyclic architectures through standard functionalization protocols, facilitating rapid library synthesis in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H314-H335
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Precautionary Statements : P210-P260-P261-P270-P271-P280-P301+P330+P331-P304+P340-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: