4-Bromo-2-chloro-5-iodopyridine

Name: 4-Bromo-2-chloro-5-iodopyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1354021-06-9
Cat. No. CS-0572408
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-chloro-5-iodopyridine|CS-0572408

Structure of 1354021-06-9

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Description

4-Bromo-2-chloro-5-iodopyridine features three halogens at distinct positions on the pyridine ring, enabling sequential cross-coupling reactions. This trihalogenated heterocycle serves as a pivotal intermediate in constructing complex pharmaceutical scaffolds and functional materials through palladium-catalyzed transformations.

Application

4-Bromo-2-chloro-5-iodopyridine serves as a versatile trihalogenated pyridine building block for cross-coupling reactions, enabling sequential functionalization in medicinal chemistry and materials science. Its orthogonal halogen reactivity supports palladium-catalyzed couplings with high selectivity, while the molecule exhibits good bench stability and ease of purification. Functions as a key scaffold intermediate in the synthesis of complex heterocyclic compounds and targeted API candidates.

General Information

CAS No. 1354021-06-9
Cat. No. CS-0572408
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂BrClIN
Molecular Weight 318.34
Synonym(s) None
SMILES IC1=CN=C(Cl)C=C1Br

Computational Chemistry Data

TPSA 12.89
LogP 3.1021
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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4-Bromo-2-chloro-5-iodopyridine

CAS No. 1354021-06-9

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