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Structure of 1356066-65-3
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This boronate-functionalized picolinonitrile features a sterically protected tetramethyl-1,3,2-dioxaborolane group that enables stable coupling under standard conditions. The electron-deficient pyridine ring pairs with the nitrile moiety to facilitate selective cross-coupling in late-stage functionalization.
3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The picolinonitrile core provides a rigid, electron-deficient heterocyclic scaffold with orthogonal functionality, enabling efficient late-stage diversification in medicinal chemistry and materials synthesis. Bench-stable and compatible with diverse reaction conditions, it facilitates rapid access to functionalized nitrile-containing heterocycles with high reproducibility and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: