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CS-W001157 4
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7-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine

  • CAS No. 1357946-27-0

  • Cat. No. CS-0334334
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine|CS-0334334

Structure of 1357946-27-0

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General Information

  • CAS No. 1357946-27-0
  • Cat. No. CS-0334334
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrIN₃
  • Molecular Weight 323.92
  • Synonym(s) None
  • SMILES C1=NC=C(C2=C1C(=NN2)I)Br

Description

7-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine is a heterocyclic building block featuring complementary halogen handles for cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via palladium-catalyzed processes, while the fused pyrazolopyridine core provides rigidity and electron-deficient character suitable for medicinal chemistry applications.

Application

7-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine serves as a versatile dual-heteroatom building block for transition-metal-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via Pd-catalyzed coupling, facilitating the construction of complex polycyclic scaffolds. Its stability under standard synthetic conditions and compatibility with diverse reaction partners make it ideal for medicinal chemistry and materials synthesis applications.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.325
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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