3-Aminopyrazolo[3,4-b]pyridine

Name: 3-Aminopyrazolo[3,4-b]pyridine
Brand: ChemScene
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CAS No. 6752-16-5
Cat. No. CS-M2176
Purity≥98%
MDL No.MFCD04113611

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 6752-16-5

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Description

3-Aminopyrazolo[3,4-b]pyridine delivers a nitrogen-rich heterocyclic scaffold with enhanced electron density at the pyrazole ring, enabling direct integration into bioactive molecule design. This bench-stable, moisture-tolerant core pairs effectively in transition-metal-catalyzed coupling reactions and serves as a strategic anchor for kinase inhibitors and fluorescent probes.

Application

3-Aminopyrazolo[3,4-b]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and catalyst development. Its fused tricyclic structure enables direct functionalization at the amine and pyridine positions, supporting diverse coupling reactions and derivatization workflows. The compound exhibits good bench stability and facilitates efficient incorporation into bioactive scaffolds due to its favorable solubility and compatibility with standard synthetic protocols.

General Information

CAS No. 6752-16-5
Cat. No. CS-M2176
Purity ≥98%
MDL No. MFCD04113611
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆N₄
Molecular Weight 134.14
Synonym(s) 1H-pyrazolo[3,4-b]pyridin-3-amine
SMILES NC1=NNC2=NC=CC=C21

Computational Chemistry Data

TPSA 67.59
LogP 0.5401
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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3-Aminopyrazolo[3,4-b]pyridine

CAS No. 6752-16-5

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