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Structure of 1359656-11-3
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5-Oxa-2-azaspiro[3.4]octane hydrochloride features a rigid spirocyclic core with embedded oxygen and nitrogen heteroatoms, delivering enhanced metabolic stability and predictable conformational behavior. This scaffold integrates readily into bioactive molecules, enabling efficient access to constrained pharmacophores in medicinal chemistry campaigns.
5-Oxa-2-azaspiro[3.4]octane hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to spirocyclic scaffolds prevalent in bioactive molecules. Its stable, crystalline form facilitates handling and purification, while the constrained spiro architecture supports high stereocontrol in downstream functionalization. The amine functionality enables facile derivatization via alkylation or acylation, and the oxacycle enhances solubility and metabolic stability in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: