tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate

Name: tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1359944-91-4
Cat. No. CS-0052933
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate|CS-0052933

Structure of 1359944-91-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate features a sterically hindered piperidine core with complementary bromo and fluorine substituents enabling selective functionalization. This bench-stable intermediate facilitates the construction of complex nitrogen heterocycles in medicinal chemistry, particularly for targeted kinase inhibitors and CNS-active compounds.

Application

tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate serves as a versatile building block for the synthesis of fluorinated piperidine scaffolds prevalent in medicinal chemistry. The molecule combines a stable tert-butyl carbamate protecting group with strategically positioned bromo and fluoro substituents, enabling orthogonal functionalization via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient access to complex heterocyclic architectures used in API development.

General Information

CAS No. 1359944-91-4
Cat. No. CS-0052933
Purity ≥96%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₇BrFNO₂
Molecular Weight 282.15
Synonym(s) None
SMILES CC(C)(C)OC(=O)N1CCC(Br)C(F)C1

Computational Chemistry Data

TPSA 29.54
LogP 2.7288
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

1359944-91-4 sigma1359944-91-4 manufacturer1359944-91-4 price1359944-91-4 structure1359944-91-4 SDSbuy 1359944-91-41359944-91-4 supplier1359944-91-4 uses1359944-91-4 molecular weightprice of 1359944-91-41359944-91-4 chemical name formula of 1359944-91-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 4-bromo-3-fluoropiperidine-1-carboxylate

CAS No. 1359944-91-4

Recommended Products