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CS-W001157 4
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3,5-Dibromo-1-methyl-1H-pyrazole

  • CAS No. 1361019-05-7

  • Cat. No. CS-0097502
  • Purity≥97%
  • MDL No.MFCD28399417
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,5-Dibromo-1-methyl-1H-pyrazole|CS-0097502

Structure of 1361019-05-7

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Description

3,5-Dibromo-1-methyl-1H-pyrazole features two bromine substituents at the 3 and 5 positions of the pyrazole ring, enhancing electrophilic reactivity. The methyl group at N1 provides steric and electronic modulation, improving stability under standard handling conditions. This bench-stable heterocycle serves as a key building block in medicinal chemistry and materials science, enabling direct coupling reactions without pre-functionalization.

Application

3,5-Dibromo-1-methyl-1H-pyrazole serves as a versatile building block for the synthesis of brominated heterocyclic scaffolds. Its regioselective substitution pattern enables efficient functionalization in cross-coupling and electrophilic aromatic substitution reactions. The methyl group enhances stability and facilitates purification, while the bromine atoms provide orthogonal handles for sequential derivatization. This compound is particularly valuable in medicinal chemistry for constructing diverse pyrazole-based pharmacophores.

General Information

  • CAS No. 1361019-05-7
  • Cat. No. CS-0097502
  • Purity ≥97%
  • MDL No. MFCD28399417
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄Br₂N₂
  • Molecular Weight 239.90
  • Synonym(s) 1H-Pyrazole, 3,5-dibromo-1-methyl-
  • SMILES CN1N=C(Br)C=C1Br

Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.9451
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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