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Structure of 1363383-18-9
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tert-Butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate features a rigid spirocyclic scaffold with a pendant hydroxyl group and a bench-stable tert-butyl carbamate. This configuration enables direct functionalization at the C7 position while maintaining structural integrity under standard reaction conditions. The molecule serves as a key intermediate in the synthesis of complex nitrogen-containing polycycles, particularly in medicinal chemistry campaigns targeting bioactive alkaloid analogs.
tert-Butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry applications, enabling efficient access to complex nitrogen-containing heterocycles. The pendant hydroxyl group offers direct handle for derivatization via esterification, etherification, or oxidation, while the tert-butyl carbamate protects the amine under standard synthetic conditions. Its stability, ease of purification, and compatibility with diverse coupling reactions make it a practical building block for target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: