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Structure of 1365957-74-9
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3-Bromo-1-methyl-1H-1,2,4-triazol-5-amine features a brominated triazole core with a methylated nitrogen at the 1-position, enabling direct incorporation into heterocyclic scaffolds. This bench-stable compound serves as a key building block for bioactive molecules in medicinal chemistry, particularly in kinase inhibitor and antifungal agent development.
3-Bromo-1-methyl-1H-1,2,4-triazol-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to triazolyl-based heterocycles via cross-coupling and nucleophilic substitution reactions. The bromo group facilitates palladium-catalyzed transformations, while the 1-methyl-1H-1,2,4-triazole scaffold offers enhanced metabolic stability and hydrogen-bonding capacity. This compound exhibits good bench stability, simplifies purification, and demonstrates broad functional group tolerance, making it well-suited for iterative synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: