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Structure of 136818-50-3
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1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid features a fused heterocyclic core with a carboxylic acid handle at the 2-position, enabling direct conjugation or derivatization. The electron-deficient pyridine ring enhances reactivity in coupling reactions, while the scaffold's planar structure supports π-stacking interactions in molecular recognition processes. This compound serves as a key building block for bioactive molecule synthesis.
1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amide coupling and decarboxylation protocols. Its carboxylic acid functionality offers direct handle for derivatization, while the fused pyrrolopyridine core provides structural rigidity and favorable pharmacophoric properties. The compound exhibits good bench stability and is compatible with common purification methods, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: