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CS-W001157 4
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4-Bromo-1H-indole-2-carboxaldehyde

  • CAS No. 1368231-70-2

  • Cat. No. CS-0040633
  • Purity≥98%
  • MDL No.MFCD22035920

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-indole-2-carboxaldehyde|CS-0040633

Structure of 1368231-70-2

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General Information

  • CAS No. 1368231-70-2
  • Cat. No. CS-0040633
  • Purity ≥98%
  • MDL No. MFCD22035920
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrNO
  • Molecular Weight 224.05
  • Synonym(s) 4-Bromo-1H-indole-2-carbaldehyde
  • SMILES O=CC(N1)=CC2=C1C=CC=C2Br

Description

4-Bromo-1H-indole-2-carboxaldehyde features a brominated indole core with a strategically positioned aldehyde group, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable, moisture-tolerant reagent facilitates efficient access to biologically active heterocycles through C–H functionalization and condensation reactions under mild conditions.

Application

4-Bromo-1H-indole-2-carboxaldehyde serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to substituted indole scaffolds. The aldehyde functionality facilitates reductive amination, Grignard additions, and Ugi-type condensations, while the bromine substituent supports palladium-catalyzed cross-coupling reactions. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for modular synthesis of bioactive molecules and heterocyclic libraries.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   2.7429
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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