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Structure of 13697-89-7
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1,3-Difluoro-2-iodobenzene is a fluorinated aryl iodide featuring complementary halogen substitution patterns that enable selective cross-coupling reactions. The ortho-iodo group facilitates palladium-catalyzed transformations, while the difluoro substitution enhances electronic tuning and metabolic stability. This molecule serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized aromatic scaffolds.
1,3-Difluoro-2-iodobenzene serves as a versatile aryl building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to substituted biaryls and heterocycles. The ortho-iodo group facilitates palladium-catalyzed coupling with high regioselectivity, while the difluoro substitution enhances metabolic stability and modulates electronic properties—making it valuable for medicinal chemistry and materials synthesis. Bench-stable and readily purified, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: