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Structure of 22280-60-0
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6-Chloro-2-methyl-3-nitropyridine features a strategically positioned nitro group and chloro substituent on a pyridine core, enabling selective functionalization in medicinal chemistry. The electron-deficient ring facilitates nucleophilic substitution, while the methyl group enhances metabolic stability. This scaffold serves as a key intermediate in developing bioactive heterocycles under standard conditions.
6-Chloro-2-methyl-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine moiety. The nitro group facilitates subsequent reduction and functionalization, while the methyl substituent provides steric and electronic modulation. This compound exhibits good bench stability and compatibility with standard synthetic protocols, making it well-suited for the construction of complex pyridine-based scaffolds in medicinal chemistry and agrochemical research.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: