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CS-W001157 4
Total: USD 88.00

tert-Butyl (16-bromohexadecyl)carbamate

  • CAS No. 1369814-75-4

  • Cat. No. CS-0910075
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (16-bromohexadecyl)carbamate|CS-0910075

Structure of 1369814-75-4

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General Information

  • CAS No. 1369814-75-4
  • Cat. No. CS-0910075
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₄₂BrNO₂
  • Molecular Weight 420.47
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCCCCCCCCCCCCCCBr

Description

tert-Butyl (16-bromohexadecyl)carbamate features a long hydrophobic alkyl chain terminated by a bromo group and a stable carbamate protecting group. This bifunctional reagent enables site-specific conjugation in peptide synthesis and surface functionalization, combining efficient coupling chemistry with excellent stability under standard conditions.

Application

tert-Butyl (16-bromohexadecyl)carbamate serves as a robust, bench-stable protecting group for primary amines in long-chain alkylamine synthesis. Its bromide functionality enables efficient post-functionalization via palladium-catalyzed cross-coupling, facilitating the construction of complex alkylated scaffolds. The tert-butyl carbamate moiety ensures high stability under diverse reaction conditions and simplifies purification through straightforward acidolysis. This reagent is particularly valuable in the synthesis of lipid-conjugated molecules and membrane-targeted pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   7.3674
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   16

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