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CS-W001157 4
Total: USD 88.00

[1,2,4]Triazolo[1,5-a]pyridine-2-carbaldehyde

  • CAS No. 1373338-09-0

  • Cat. No. CS-W021189
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[1,2,4]Triazolo[1,5-a]pyridine-2-carbaldehyde|CS-W021189

Structure of 1373338-09-0

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General Information

  • CAS No. 1373338-09-0
  • Cat. No. CS-W021189
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O
  • Molecular Weight 147.13
  • Synonym(s) [1,2,4]Triazolo[1,5-a]pyridine-2-carboxaldehyde
  • SMILES O=CC1=NN2C=CC=CC2=N1

Description

[1,2,4]Triazolo[1,5-a]pyridine-2-carbaldehyde features a rigid heteroaromatic core fused with an aldehyde functionality, enabling direct incorporation into conjugation workflows. This electron-deficient scaffold supports efficient transition-metal-catalyzed coupling reactions and serves as a key building block in bioactive molecule design.

Application

[1,2,4]Triazolo[1,5-a]pyridine-2-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocyclic scaffolds. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and condensation reactions under mild conditions, while the fused triazolopyridine core offers enhanced metabolic stability and favorable binding interactions. The compound exhibits excellent bench stability and compatibility with common functional groups, supporting scalable synthesis and purification via standard chromatographic methods.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.26
  • LogP   0.5418
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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