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CS-W001157 4
Total: USD 88.00

Oxetan-3-ylhydrazine dihydrochloride

  • CAS No. 1374652-22-8

  • Cat. No. CS-0187598
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Oxetan-3-ylhydrazine dihydrochloride|CS-0187598

Structure of 1374652-22-8

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Description

Oxetan-3-ylhydrazine dihydrochloride delivers a reactive oxetane ring fused to a hydrazine moiety, enabling efficient conjugation under mild conditions. This bench-stable reagent facilitates site-specific bioconjugation and integration into dynamic covalent systems, offering enhanced solubility and controlled reactivity in aqueous environments.

Application

Oxetan-3-ylhydrazine dihydrochloride serves as a versatile building block for the construction of oxetane-containing heterocycles and bioactive molecules. Its hydrazine functionality enables direct coupling with carbonyl compounds, facilitating the synthesis of hydrazones under mild conditions. The oxetane ring imparts enhanced metabolic stability and improved solubility, making it valuable in medicinal chemistry applications. The dihydrochloride salt ensures excellent bench stability, ease of handling, and straightforward purification in standard synthetic workflows.

General Information

  • CAS No. 1374652-22-8
  • Cat. No. CS-0187598
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₁₀Cl₂N₂O
  • Molecular Weight 161.03
  • Synonym(s) 1-(oxetan-3-yl)hydrazine dihydrochloride
  • SMILES C1C(CO1)NN.Cl.Cl

Computational Chemistry Data

  • TPSA   47.28
  • LogP   -0.3079
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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