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Structure of 40004-08-8
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Ethyl 2-(piperazin-1-yl)acetate features a piperazine ring linked to an ethyl ester-functionalized acetyl moiety, delivering enhanced solubility and nucleophilicity. This bifunctional scaffold integrates readily into medicinal chemistry libraries, serving as a key intermediate for bioactive compound synthesis. The molecule exhibits bench-stable handling under standard conditions.
Ethyl 2-(piperazin-1-yl)acetate serves as a versatile bifunctional building block in medicinal chemistry, enabling the synthesis of piperazine-containing scaffolds prevalent in pharmaceuticals. The ester group facilitates straightforward derivatization via hydrolysis or nucleophilic substitution, while the pendant piperazine nitrogen supports salt formation and hydrogen bonding in drug-target interactions. Its bench-stable nature and compatibility with standard coupling protocols make it a practical choice for iterative compound library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: