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Structure of 1375964-39-8
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3-Bromo-2-fluorophenylacetic acid features a bromo and fluoro substituent positioned ortho to the acetic acid side chain on a phenyl ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This combination enables direct incorporation into pharmaceutical intermediates requiring halogenated aromatic platforms, particularly in kinase inhibitor scaffolds and bioactive heterocycles. The molecule exhibits excellent solubility in common organic solvents and maintains stability under standard bench conditions.
3-Bromo-2-fluorophenylacetic acid serves as a valuable building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted benzene derivatives via standard coupling reactions. Its orthogonal halogenation pattern facilitates selective functionalization, while the carboxylic acid group supports direct derivatization or activation. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: