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Structure of 1379812-12-0
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tert-Butyl 3-(nitromethylidene)azetidine-1-carboxylate features a strained azetidine ring bearing a nitromethylidene group, delivering high reactivity for cycloaddition and functionalization. This bench-stable, moisture-tolerant building block integrates efficiently into complex heterocycles and enables rapid access to nitrogen-rich scaffolds under mild conditions.
tert-Butyl 3-(nitromethylidene)azetidine-1-carboxylate serves as a versatile building block for the synthesis of azetidine-containing scaffolds, enabling efficient access to nitrogen heterocycles via nitro group reduction and subsequent functionalization. Its stability under standard reaction conditions, combined with tolerance for diverse transformations, facilitates straightforward incorporation into medicinal chemistry campaigns. The protected azetidine core supports modular derivatization and is compatible with common coupling and cyclization protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: