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Structure of 882500-21-2
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5-Bromo-6-trifluoromethylpyridin-2-ylamine features a pyridine core bearing bromo and trifluoromethyl groups at adjacent positions, enabling selective cross-coupling reactions. The primary amine facilitates direct functionalization in C–N bond formation, while the electron-deficient aromatic ring enhances reactivity in palladium-catalyzed transformations. This scaffold offers high stability under standard conditions and compatibility with diverse reaction media.
5-Bromo-6-trifluoromethylpyridin-2-ylamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo substituent. The trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the primary amine facilitates derivatization and incorporation into diverse heterocyclic scaffolds. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: