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Structure of 1381957-27-2
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Methyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzoate features a boronate ester group that enables reliable Suzuki-Miyaura cross-coupling under mild conditions. The tetramethylcycloborane moiety ensures high stability and moisture tolerance, while the methyl benzoate functionality provides solubility in common organic solvents. This compound serves as a key building block for conjugated aryl systems in pharmaceutical and materials synthesis.
Methyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzoate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl halides and pseudohalides under mild conditions, offering excellent functional group tolerance and bench stability. This reagent facilitates the construction of biaryl scaffolds commonly found in pharmaceutical intermediates and materials chemistry, with straightforward purification and compatibility across scale-up workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: