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Structure of 138498-97-2
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2-(Tetrahydrofuran-3-yl)acetic acid features a tetrahydrofuran ring tethered to a carboxylic acid-bearing acetyl side chain, combining heterocyclic rigidity with reactive functionality. This structure enables integration into chiral building blocks and bioactive molecule scaffolds, offering enhanced solubility and metabolic stability in synthetic pathways.
2-(Tetrahydrofuran-3-yl)acetic acid serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its tetrahydrofuran ring imparts conformational rigidity and metabolic stability, while the carboxylic acid group facilitates direct derivatization or coupling reactions. The molecule exhibits excellent bench stability, compatibility with standard protecting group strategies, and ease of purification—making it well-suited for iterative synthesis and scale-up applications in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: