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Structure of 85064-61-5
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Tetrahydro-2H-pyran-4-ylacetic acid features a hydrolytically stable tetrahydropyran ring that confers enhanced solubility and metabolic stability. This scaffold integrates a pendant acetic acid group, enabling direct conjugation or derivatization in synthetic workflows. The protected alcohol moiety facilitates selective transformations under mild conditions.
Tetrahydro-2H-pyran-4-ylacetic acid serves as a versatile building block in medicinal chemistry, offering a protected hydroxyl group and a carboxylic acid functionality for orthogonal derivatization. The tetrahydropyranyl (THP) moiety provides excellent stability under acidic conditions and facilitates selective deprotection, enabling controlled functionalization. This compound enables efficient synthesis of complex heterocyclic scaffolds and bioactive intermediates, with favorable handling properties and compatibility in standard peptide coupling and conjugation workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: