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Structure of 138563-54-9
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3,4-Difluoro-N-methylaniline features a fluorinated aromatic ring paired with a methylaniline side chain, delivering enhanced electron density and improved metabolic stability. This combination enables efficient incorporation into bioactive scaffolds and facilitates selective coupling reactions under mild conditions.
3,4-Difluoro-N-methylaniline serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds through standard coupling reactions. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the N-methyl group improves lipophilicity and membrane permeability. The compound exhibits good bench stability and is compatible with common reaction conditions, facilitating straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2922
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Class : 8 (6.1)
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Packing Group : Ⅲ
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Hazard Statements : H227-H301-H315-H317-H318-H335-H412
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Precautionary Statements : P210-P235-P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: