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Structure of 13924-94-2
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Methyl 5-aminopyrazine-2-carboxylate features a pyrazine core functionalized with an amino group at the 5-position and a methyl ester at the 2-position. This electron-rich heterocycle integrates readily into synthetic routes for pharmaceutical intermediates, offering enhanced solubility and stability under standard conditions.
Methyl 5-aminopyrazine-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. The pyrazine core provides a rigid, electron-deficient platform amenable to palladium-catalyzed cross-coupling reactions. The amino and ester functionalities enable sequential derivatization—enabling access to diverse analogs via amidation, alkylation, or cyclization—while exhibiting good bench stability and straightforward purification by standard chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: