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Structure of 1393524-00-9
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This chiral carbamate features a bench-stable trifluoromethyl group flanked by a hydroxy-bearing stereocenter, enabling selective protection of amines in complex synthesis. The tert-butyl moiety provides orthogonal deprotection under mild acidic conditions, while the (S)-configuration ensures high stereochemical fidelity in asymmetric transformations.
tert-Butyl (S)-(1,1,1-trifluoro-3-hydroxypropan-2-yl)carbamate serves as a chiral building block for fluorinated synthons, enabling access to trifluoromethylated amino alcohols via mild deprotection. The protected hydroxyl group exhibits excellent bench stability and compatibility with diverse functional groups, facilitating its use in iterative synthesis of complex fluorinated scaffolds. Its orthogonal reactivity profile supports selective transformations in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: