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Structure of 139399-61-4
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2-Bromoquinolin-8-ol features a bromine atom at the C2 position and a hydroxyl group at C8, creating a unique scaffold for transition-metal-catalyzed cross-coupling reactions. This electron-deficient heterocycle integrates readily into complex molecular architectures under standard conditions.
2-Bromoquinolin-8-ol serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality and phenolic hydroxyl group. The molecule exhibits good bench stability and facilitates efficient derivatization in medicinal chemistry workflows, particularly for constructing quinoline-based scaffolds found in kinase inhibitors and antimalarial agents. Its compatibility with standard coupling conditions supports scalable synthesis and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: