Pyridine-2,6-dicarboxamidine dihydrochloride

Name: Pyridine-2,6-dicarboxamidine dihydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1394382-56-9
Cat. No. CS-0309755
Purity≥98%
MDL No.MFCD31718854

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Pyridine-2,6-dicarboxamidine dihydrochloride|CS-0309755

Structure of 1394382-56-9

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Application

Pyridine-2,6-dicarboxamidine dihydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of nitrogen-rich heterocycles. Its amidine functionality offers strong hydrogen-bonding capacity and enhanced solubility, facilitating downstream derivatization in SPPS and macrocycle synthesis. The dihydrochloride salt form ensures excellent bench stability and ease of handling, while the pyridine core provides a rigid scaffold for structure-activity studies. Functions effectively in transition-metal-catalyzed couplings and amide bond formations under standard reaction conditions.

General Information

CAS No. 1394382-56-9
Cat. No. CS-0309755
Purity ≥98%
MDL No. MFCD31718854
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₁Cl₂N₅
Molecular Weight 236.11
Synonym(s) None
SMILES NC(C1=NC(C(N)=N)=CC=C1)=N.Cl.Cl

Computational Chemistry Data

TPSA 112.63
LogP 0.49334
H_Acceptors 3
H_Donors 4
Rotatable_Bonds 2

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Material Science Covalent Organic Frameworks Amido COFs Linkers

Catalysts and Ligands Ligands Pyridine Ligands Monopyridine Ligands

Material Science Material Building Blocks Covalent Organic Frameworks (COFs) Linkers Amine Linkers

Material Science Polymer/Macromolecule Reagents Covalent Organic Frameworks (COFs) Linkers Amine Linkers

Catalysis Nitrogen-Donor Ligands Pyridine Ligands

Catalysis Nitrogen-Donor Ligands Bipyridine Ligands, Terpyridine Ligands

Key Words

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Pyridine-2,6-dicarboxamidine dihydrochloride

CAS No. 1394382-56-9

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