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CS-W001157 4
Total: USD 88.00

3-Hydroxy-4-methoxy-4-oxobutanoic acid

  • CAS No. 140235-34-3

  • Cat. No. CS-0571278
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-4-methoxy-4-oxobutanoic acid|CS-0571278

Structure of 140235-34-3

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General Information

  • CAS No. 140235-34-3
  • Cat. No. CS-0571278
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₅
  • Molecular Weight 148.11
  • Synonym(s) 2-Hydroxysuccinic Acid Methyl Ester
  • SMILES COC(=O)C(CC(=O)O)O

Synthesis

  • Route1
    • null|null
      67-56-1
    • null|null
      617-48-1
    • ~72%
    • 3-Hydroxy-4-methoxy-4-oxobutanoic acid|CS-0571278
      140235-34-3

    References

    • Houston, Todd A.; Wilkinson, Brendan L.; Blanchfield, Joanne T. Organic Letters, 2004 , vol. 6, # 5 p. 679 - 681
  • Route2
    • null|null
      67-56-1
    • (R)-2-Hydroxysuccinic acid  Cabozantinib Impurity|CS-0167005
      636-61-3
    • ~65%
    • 3-Hydroxy-4-methoxy-4-oxobutanoic acid|CS-0571278
      140235-34-3

    References

    • University of Notre Dame du Lac Patent: US4992544 A1, 1991 ; US 4992544 A
  • Route3
    • null|null
      67-56-1
    • null|null
      83477-75-2
    • ~%
    • 3-Hydroxy-4-methoxy-4-oxobutanoic acid|CS-0571278
      140235-34-3

    References

    • Liljeblad, Arto; Aksela, Reijo; Kanerva, Liisa T. Tetrahedron Asymmetry, 2001 , vol. 12, # 14 p. 2059 - 2066

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.83
  • LogP   -1.005
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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