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CS-W001157 4
Total: USD 88.00

4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride

  • CAS No. 1403864-74-3

  • Cat. No. CS-W006164
  • Purity≥98%
  • MDL No.MFCD26406403

*For research and further manufacturing use only, not for direct human use.

4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride|CS-W006164

Structure of 1403864-74-3

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General Information

  • CAS No. 1403864-74-3
  • Cat. No. CS-W006164
  • Purity ≥98%
  • MDL No. MFCD26406403
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆ClNO
  • Molecular Weight 177.67
  • Synonym(s) 4-AMINOBICYCLO[2.2.2]OCTAN-1-OL HCL
  • SMILES OC1(CC2)CCC2(N)CC1.Cl

Description

4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is a bench-stable, moisture-tolerant crystalline solid featuring a rigid bicyclic scaffold that positions the primary amine and hydroxyl groups in defined spatial orientation. This structural rigidity enhances its utility as a chiral building block in medicinal chemistry and asymmetric synthesis.

Application

4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride serves as a rigid, conformationally constrained scaffold for medicinal chemistry applications. Its tertiary alcohol and primary amine functionalities enable straightforward derivatization, while the bicyclic core imparts metabolic stability and defined spatial orientation. The hydrochloride salt enhances solubility and handling, facilitating use in standard coupling, alkylation, and acylation reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.2046
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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