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Structure of 14080-51-4
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2-Aminothiophene-3-carboxamide features a fused thiophene core with strategically positioned amino and carboxamide groups, enabling versatile integration into bioactive scaffolds. This electron-rich heterocycle supports hydrogen bonding and dipole interactions, enhancing target affinity in medicinal chemistry applications. The compound exhibits bench-stable handling characteristics and facilitates efficient derivatization under standard conditions.
2-Aminothiophene-3-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard coupling and cyclization reactions. Its dual functionality—amine and amide groups—supports diverse derivatization, including amidation, urea formation, and transition-metal-catalyzed cross-couplings. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other pharmacologically relevant architectures.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H317-H319
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: