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CS-W001157 4
Total: USD 88.00

cis-3-Fluorocyclobutanamine hydrochloride

  • CAS No. 1408075-13-7

  • Cat. No. CS-0049708
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

cis-3-Fluorocyclobutanamine hydrochloride|CS-0049708

Structure of 1408075-13-7

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General Information

  • CAS No. 1408075-13-7
  • Cat. No. CS-0049708
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClFN
  • Molecular Weight 125.57
  • Synonym(s) None
  • SMILES Cl.N[C@H]1C[C@@H](F)C1

Description

cis-3-Fluorocyclobutanamine hydrochloride offers a rigid, conformationally constrained scaffold ideal for probing bioactive amine interactions. The fluorine atom at the 3-position imparts enhanced metabolic stability and modulates electronic properties, while the hydrochloride salt ensures excellent solubility and handling convenience in aqueous reaction media.

Application

cis-3-Fluorocyclobutanamine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated cyclobutane scaffolds prevalent in bioactive molecules. Its stability, ease of handling, and compatibility with standard amine transformations facilitate efficient incorporation into target compounds. Functions as a versatile intermediate for peptide analogs and heterocyclic systems, particularly where constrained ring structures and stereoselective fluorination are required.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.8674
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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