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Structure of 140914-89-2
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2-(Pyrazin-2-yl)acetic acid features a pyrazine ring conjugated to a carboxylic acid-bearing side chain, enabling robust integration into bioconjugation and medicinal chemistry scaffolds. The electron-deficient pyrazine core enhances reactivity in nucleophilic substitution processes, while the pendant acetic acid group offers facile derivatization for peptide coupling or metal chelation. This structure supports modular synthesis of functionalized heterocycles under standard bench conditions.
2-(Pyrazin-2-yl)acetic acid serves as a versatile building block for constructing bioactive heterocycles and pharmaceutical scaffolds. Its pyrazine core enables robust π–π stacking and hydrogen-bonding interactions in target binding, while the pendant carboxylic acid facilitates direct coupling or derivatization. The compound exhibits good bench stability and compatibility with standard amide coupling protocols, enabling efficient access to peptide-like conjugates and macrocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: