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CS-W001157 4
Total: USD 88.00

2,6-Diaminopyridine

  • CAS No. 141-86-6

  • Cat. No. CS-W020019
  • Purity≥98%
  • MDL No.MFCD00006329

*For research and further manufacturing use only, not for direct human use.

2,6-Diaminopyridine|CS-W020019

Structure of 141-86-6

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General Information

  • CAS No. 141-86-6
  • Cat. No. CS-W020019
  • Purity ≥98%
  • MDL No. MFCD00006329
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃
  • Molecular Weight 109.13
  • Synonym(s) None
  • SMILES NC1=NC(N)=CC=C1

Description

Azido-PEG2-NHS ester is a click chemistry crosslinker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Synthesis

  • Route1

    References

    • Mackewitz, Thomas; Volland, Martin; Paciello, Rocco; Schafer, Ansgar; Breit, Bernhard; Seiche, Wolfgang Patent: US2004/199024 A1, 2004 ; Location in patent: Page 17 ;
  • Route2

    References

    • E. I. DU PONT DE NEMOURS AND COMPANY Patent: WO2009/18504 A1, 2009 ; Location in patent: Page/Page column 19 ;
  • Route3

    References

    • Liao, Bei-Sih; Liu, Shiuh-Tzung Journal of Organic Chemistry, 2012 , vol. 77, # 15 p. 6653 - 6656

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.93
  • LogP   0.246
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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