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Structure of 141577-92-6
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Pyrrolidine-1-sulfonyl fluoride is a bench-stable fluorosulfonyl reagent featuring a cyclic amine scaffold that enables selective sulfonation of nucleophiles. This electrophilic fluorosulfonyl group integrates readily into bioactive molecules, offering enhanced metabolic stability and improved solubility in medicinal chemistry applications.
Pyrrolidine-1-sulfonyl fluoride serves as a versatile electrophilic sulfonylating agent, enabling efficient introduction of sulfonamide groups under mild conditions. Its high reactivity with nucleophiles—particularly amines and alcohols—facilitates rapid access to sulfonamide derivatives, commonly employed in medicinal chemistry scaffolds. The compound exhibits bench stability, ease of handling, and compatibility with diverse functional groups, making it ideal for modular synthesis workflows and late-stage functionalization.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: