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Structure of 1416244-48-8
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This difluorinated boronic acid integrates a methyl-substituted aryl moiety with enhanced stability and improved solubility in polar solvents. The ortho-fluoro groups facilitate efficient Suzuki-Miyaura coupling, enabling rapid construction of complex biaryl architectures under standard conditions.
(4,5-Difluoro-2-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-fluoro substituents enhance stability and modulate reactivity, while the methyl group provides steric and electronic tuning for downstream functionalization. The boronic acid is bench-stable, readily purified by recrystallization, and compatible with diverse reaction matrices, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: